Julie Arslanoglu, The Metropolitan Museum of Art, USA
Julie Arslanoglu joined the Department of Scientific Research at The Metropolitan Museum of Art in in 2006. She investigates the organic materials of paints, coatings, and adhesives, using mass-spectrometric and immunological techniques, with emphasis on natural and synthetic polymer identification and degradation. She introduced routine identification and localization antibody-based methods at the Metropolitan Museum to study artworks and in 2010 was awarded an NSF grant to study the impact of age, pigments and environment on protein-based paints and their identification by these methods. In 2018, with the NYU Conservation Center, she organized an international, highly interactive meeting (ART BIO MATTERS 2018 (Lounsbury Foundation)), focused on informing about the scientific capabilities for biological material study and debating their alignment with curatorial, conservation and art historical interests in biological materials related to artworks. She has a graduate degree is in organic chemistry from the Pennsylvania State University and a postgraduate degree in paintings conservation from the Courtauld Institute of Art. She has held positions at the Getty Conservation Institute, the Victoria & Albert Museum, the University of Texas at San Antonio, and the National Institutes of Health. She and her collaborator Prof. Caroline Tokarski from the University of Bordeaux, hold International Laboratory (LIA) status through the National Center for Scientific Research (CNRS) of France for the development and implementation of new mass-spectrometry protocols and strategies for the research of organic polymeric materials in cultural heritage.
Leila Birolo, University of Naples, Italy
Leila Birolo obtained a degree in Chemistry and a PhD in Chemical Sciences at the University of Naples "Federico II", working since then on protein chemistry. After a Post-doctoral fellow at the Dep. of Biochemistry Wales University, Cardiff, U.K and several Post-docs, moving from enzymology to conformational analysis of proteins by mass spectrometric approaches and to proteomics, in 2000 she was enrolled as Researcher and since 2005 as Associate Professor of Biochemistry at the University of Naples "Federico II". In the late years of the first decade of 2000s she started applying proteomics to cultural heritage, adapting methodologies and protocols to the specific typology of samples. Leila has been involved in many research projects granted by MIUR and EU, the latest of which is a four years MARIE SKŁODOWSKA-CURIE ITN., H2020 (Grant Agreement No. 722606) TEMPERA: Teaching Emerging Methods in Palaeoproteomics for the European Research Area.
Ilaria Bonaduce, University of Pisa, Italy
Ilaria Bonaduce received her Ph.D. in Chemical Science in 2006 and is currently Associate Professor in Analytical Chemistry at the Department of Chemistry and Industrial Chemistry, University of Pisa. She teaches undergraduate and Masters level lecture courses, and associated practical courses, in Analytical Chemistry. Her research centres on understanding modifications undergone by organic materials in paint and archaeological polychrome artifacts as an effect of pre-treatments, ageing and interaction with other organic and inorganic materials, with particular focus on lipids and proteins. On these grounds she works on three main research lines: i) the development of analytical methodologies and procedures, based on mass spectrometry (GC-MS, Py-GC-MS, HPLC-MS and proteomics), as well as analytical models for data interpretation, aimed at the reliable identification of organic materials in art and archaeological samples; ii) understanding the physicochemical behaviour of paint layers to aid the further development of appropriate conservation and preservation strategies; iii) the characterisation of organic materials in paintings and archaeological polychrome artifacts, to reconstruct artistic techniques and technologies of the past. This research has resulted in over 70 peer reviewed scientific publications.
Ilaria Bonaduce has been actively participating in several national and international projects. Of these she has been coordinator of a FP7-PEOPLE-2009-IEF project (project ID 253831: Saccharide Materials in Paint Systems: Nature, Occurrence and Physicochemical Evolution) granted by EC 7th framework programme, principal investigator of the Italian unit of the project CMOP - JPI Cultural Heritage Call "Heritage+; Transnational collaborative research project. 2015-2018, and member of the research teams of the FP7-MEMORI- Measurement, Effect Assessment and Mitigation of Pollutant Impact on Movable Cultural Assets – Innovative Research for Market Transfer", the FP6 - PROPAINT Improved protection of paintings during exhibition, storage and transit.
Enrico Cappellini, Natural History Museum of Denmark, University of Copenhagen, Denmark
Enrico Cappellini uses high-resolution tandem mass spectrometry (MS) to sequence ancient protein residues recovered from paleontological and cultural heritage materials. He is actively involved in methodological development to push reliable recovery of ancient proteins further back in time, to minimise starting sample quantities and to improve data analysis and interpretation.
Initially trained in biochemistry and molecular biology at the University of Turin (Italy), Enrico Cappellini expanded his expertise in ancient biomolecules investigation during his doctoral research studies at the University of Florence (Italy), focusing on the analysis of ancient DNA from archaeological human remains. During his post-doctoral activity at the University of York (UK), he continued working on ancient DNA and started focusing on the analysis of ancient protein residues by amino acid racemisation analysis and MS-based proteomics. He moved to the University of Copenhagen (DK) where he continues to apply proteomics techniques to ancient samples, together with his colleagues, to describe multiple ancient proteomes and metaproteomes.
Matthew Collins, University of Cambridge, England and Natural History Museum of Denmark, University of Copenhagen, Denmark
Matthew Collins, FBA is a Niels Bohr Professor at the University of Copenhagen (60%) and the McDonald Chair of Palaeoproteomics, based at the McDonald Institute for Archaeological Research within the Department of Archaeology and Anthropology. (40%). He previously founded BioArCh, a biomolecular archaeology group at the University of York collaboration between the departments of biology, chemistry and archaeology (BioArCh: Biology Archaeology, Chemistry).
In 2014 he was elected a Fellow of the British Academy, the United Kingdom's national academy for the humanities and social sciences.
He conduct research on the persistence of proteins in ancient samples, using modelling to explore the racemization of amino acids and thermal history to predict the survival of DNA and other molecules. Using a combination of approaches (including immunology and protein mass spectrometry) his research detects and interprets protein remnants in archaeological and fossil remains.
He developed ZooMS (Zooarchaeology by Mass Spectrometry) a way to rapidly identify bone and other collagen based materials using peptide mass fingerprinting.
Garry Corthals, University of Amsterdam, The Netherlands
Garry Corthals is Chair and professor of Biomolecular Systems Analytics at the University of Amsterdam (UvA), visiting professor at M4I of Maastricht University and guest professor at the Amsterdam UMC. His laboratory develops and applies mass spectrometry methods and computational tools to measure proteomes of clinical samples as well as other molecular systems. His current interests lie in fast quantitative proteome analysis that enables knowledge-representation of patient samples for classification, diagnosis and prognosis. Through developments in ambient ionisation for fast MS analysis his group have started new research lines into 'Science for Art' and Forensics, where rich molecular MS analysis over the course of minutes. Prior to his work in Amsterdam Garry Corthals has held leading positions at University of Turku & Centre for Biotechnology (Finland), Geneva University Hospital (Switzerland), the Garvan Institute for Medical Research (Australia), and the University of Washington (Seattle, USA). In the past he was Chair of several national and international large-scale facilities offering development, services and outreach for Proteomics and Metabolomics. He was a founder of the European Proteomics Association (EuPA) where he held serval posts and is the current Chair of HUPO’s Education & Training.
Jürgen Cox, Max Planck Institute, Germany
Jürgen Cox, Full Professor and PI, is a world leading authority on computational proteomics, he is best known as the creator of the MaxQuant suite of computational proteomics algorithms and software programs, which have revolutionized the field of quantitative, high resolution proteomics. As has happened in biological fields many times before, Prof. Cox was originally trained as a theoretical physicist. He obtained his master's degree from the University of Aachen. He worked on computational modeling in statistical and particle field theory, for his PhD degree, which he obtained from the Massachusetts Institute of Technology (MIT) in Cambridge, US, in 2001. He is the coordinator of the MaxQuant summer school and supervised several PhD and Master students from all over the world.
Christian Kelstrup, Novo Nordisk Foundation Center for Protein Research, Denmark
Christian Kelstrup is Associate Professor in Mass Spectrometry-based Proteomics and is pushing technological developments within the group of Dr Jesper V Olsen. He have optimized widely used MS methods, co-developed the latest MS instrumentation, developed frameworks for studying non-tryptic, endogenous peptides with modifications (Secher & Kelstrup et al., Nat. Commun., 2016), and contributed to several studies within the field of ancient proteomics (Orlando et al., Nature, 2013; Warinner et al. Nat. Genet.,2014).
Katrien Keune, Rijksmuseum, Amsterdam, The Netherlands
Katrien Keune received her degree in Chemistry at the University of Amsterdam (UvA) in 2000 and got her PhD degree in Analytical Chemistry in 2005. Keune was a postgraduate research fellow (supported by NWO Talent-fellowship) at the Scientific Department of the National Gallery in London (2006-2007). Currently, she is the head of science department at the Rijksmuseum Amsterdam, Netherlands. She also holds an appointment as Associate Professor of Chemistry at the University of Amsterdam (UvA) and contributes to the Netherlands Institute for Conservation, Art and Science (NICAS) at a scientific and organizational level. She is responsible for carrying out and developing scientific research projects with and providing analytical support to the conservation studios of the Rijksmuseum. The research is carried out in close collaboration with conservators, art historians and curators. She is specialized in ageing and degradation studies of pigments and oil paintings at the micro- and molecular level, especially related to pigment-binding medium interactions. She has (co-)authored to many publications focusing on degradation phenomena in oil paintings and is co-editor of the book ‘Metal Soaps in Art’ (2019, Springer). She participates and participated in (inter)national research projects and is co-supervising various PhD-students and post-docs.
Michel Menu, Centre de Recherche et de Restauration des Musées de France, France
Michel Menu is head of the Research of the Centre de Recherche et de Restauration des Musées de France C2RMF, and co-responsible of the team working on Cultural Heritage in UMR CNRS 8247, Institut de Recherche de Chimie Paris. He has a strong expertise in the structural study of inorganic material using mainly X-ray and ion beam techniques. His main concern consists to bridge the different discipline in order to foster the insertion of the material studies inside the art history and conservation disciplines. He is French coordinator or European projects “Integrated Infractrusture Initiatives”: LABSTECH (2001-2004), Eu-Artech (2004-2009), CHARISMA (2009-2014), Iperion (2015-2019). He is the Editor-in-Chief of the Technè journal and member of the editorial board of Applied Physics A. He published 228 scientific papers and 20 books or book chapters.
Caroline Tokarski, University of Bordeaux-CNRS, France
Caroline Tokarski is Professor at the University of Bordeaux, UMR CNRS 5248 CBMN. She is member of the Institut Universitaire de France and nominated member of the CNRS national committee. She was recently nominated corresponding member of the National Academy of Pharmacy. She is head of the Proteome Plateform of Bordeaux and co-head of the CNRS Associated International Laboratory ARCHE (ARt and Cultural HEritage: Natural Organic Polymers by Mass Spectrometry) with Julie Arslanoglu, the Metropolitan Museum of Art, New York. Her research activities are focused on the study of organic (bio)macromolecules from native or transformed samples using high resolution mass spectrometry. She published the first application of proteomics in Cultural Heritage. She also proposed high resolution omics methods to identify accurately proteins, lipids and polysaccharides, their modifications and their biological origins. She was recognized in 2011 by the Analytical Chemistry Division of the French Society of Chemistry for her developments in Mass Spectrometry for Cultural Heritage (Award 2011). Her current developments are focused on intact protein analysis (top down) and networking/crosslinkings/modifications of organic macromolecules as well as their interactions with their matrices (art and archaeological materials).
Klaas Jan van den Berg, Cultural Heritage Agency of the Netherlands, Amsterdam, The Netherlands
Klaas Jan van den Berg is a senior conservation scientist based at the Cultural Heritage Agency of the Netherlands since 2000. He received his PhD in Chemistry at the University of Amsterdam in 1994. From 1995 to 1999 he was a project leader in MOLART in charge of the development of strategies for chemical analysis (both bulk and surface) of painting materials. Since June 2016, he is a part-time full professor in Conservation Science (Painted Art) at the University of Amsterdam.
His current main focus is the chemical and optical study of the changing paint surface, in relation to paint formulations, application techniques and surface cleaning in 20th Century oil paintings. Archival studies comprise primarily the exploration of the Royal Talens production archive, which is a rich source of actual paint compositions over the years, information on historical materials suppliers, production philosophy and development. Studies on the degradation of oil paints include those on efflorescence and solvent-sensitive oil paintings, and conservation research into alternative surface cleaning methodology. For the analysis of oil paints, he employs a range of MS techniques including Direct Temperature-resolved mass spectrometry, GCMS and FIA and LC- Electrospray Ionisation MS.
Klaas Jan van den Berg wrote or is involved in over 140 publications. He is an editor of journals and books on conservation and conservation science related topics.
Philippe Walter, Sorbonne Université-CNRS, Paris, France
Philippe Walter is director of research at CNRS and head of the Laboratory of molecular and structural archaeology (Sorbonne Université/CNRS) in Paris, France. He develops new instruments and analytical techniques adapted to the in situ and non-invasive study of ancient materials. His main research interests are focused on the use of analytical chemistry to understand the development of chemistry to create health and beauty products during Antiquity as well as pigments, binders and medium useful for the Old Masters. He is the holder of a PhD degree from Paul Sabatier University, Toulouse. Working at CNRS since 1995, he was the recipient of the CNRS silver medal in 2008 and the Grand Prix le Bel of the Societe Chimique de France in 2017. He was appointed Professor at College de France for the academic year 2013-2014, holder of the Chair of Innovative Technology.